Sae End Date

Sae End Date Start date First day with any adverse symptoms or a clear deterioration of a pre existing condition For example the onset of an event may occur before a hospitalisation Stop date

The clinical team creates the SAE visit in CTMS within 24 hours of notification of the SAE When Research Financial Operations is notified that an SAE is related to a drug or device that notification begins the SAE tracking Record the date of resolution in DD MMM YYYYformat If the SAE is ongoing at the end of the study check the Ongoing at end of study box

Sae End Date

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Safety Reporting Current section refers to the item 4 11 Safety Reporting of the INTEGRATED ADDENDUM TO ICH E6 R1 GUIDELINE FOR GOOD CLINICAL PRACTICE E6 R2 It This section presents information related to adverse event AE reporting and safety monitoring in HPTN 094 The following resources are relevant to AE reporting DAIDS Table for Grading

SAE end stop date SAE end date is the date of AE recovery What is NOT an SAE Hospital admissions planned for Any intervention or surgery planned before study entry or for social The end of the study is defined as the stopping date or x date and not the end of data close out Data analysis will separate out any SAEs occurring before the start of study

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An SAE report form contains information such as the event onset date date that it became serious and end date seriousness criteria resulted in death was life threatening required Dataset displayed below shows the AE of interest start date end date and first dose date So the time to onset is calculated as the difference between ae start date and first dose date

5 Brief description of participants with no personal identifiers Sex F M Age Diagnosis for study participation 6 Brief description of the nature of the SAE attach Serious Adverse Event SAE Any adverse event that Results in death Is life threatening or places the participant at immediate risk of death from the event as it occurred Requires or

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Serious Adverse Event SAE Form Clinical Trials

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Start date First day with any adverse symptoms or a clear deterioration of a pre existing condition For example the onset of an event may occur before a hospitalisation Stop date

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Operationalizing The Serious Adverse Event SAE

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The clinical team creates the SAE visit in CTMS within 24 hours of notification of the SAE When Research Financial Operations is notified that an SAE is related to a drug or device that notification begins the SAE tracking


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Sae End Date - In this case the adverse event end date of January 5 2001 is before the treatment start date of January 7 2001 and would therefore indicate that the adverse event is